button cancel
Poskusite iskati po ključnih besedah, šifri izdelka ali številki naročila ali serijski številki, npr. „CM442“ ali „tehnične informacije“
Za začetek iskanja vnesite vsaj dva znaka.
  • Zgodovina

Raman upstream bioprocess control

Nicro provides turnkey solutions for fermenters

This case study examines how Nicro moved from time-consuming sample analysis to real-time monitoring of critical parameters in their fermentation processes. The result? Inline process monitoring of metabolites without the need of offline sampling helped the company improve process control, leading to optimized production and increased yield.

Bioreactors in Nicro case study ©Endress+Hauser

The results

  • Faster process cycle times with less risk due to in-line,
    real-time process monitoring of metabolites

  • Improved process control leading to optimized
    production and increased yield

  • A complete technology packaged solution for fermentation processes

Customer challenges

A typical indicator of fermentation progress is the lack of dissolved oxygen in the media which gives an estimation of the process duration. Optical density and metabolites may also be monitored for better insight into the process. Concentration of metabolites would usually be measured off-line with time-consuming chromatographic techniques. This off-line sampling approach can bring a potential risk of contamination and lead to the loss of a valuable batch.

Our solution

Nicro combined its competencies together with BICRO BIOCentre and Endress+Hauser to provide a complete packaged solution for fermentation processes. It includes:

  • Engineering and design of a complete fermentation system from Nicro

  • An Endress+Hauser Raman Rxn analyzer and Rxn-45 probe, powered by Kaiser Raman technology

  • Analytical services from BICRO BIOCentre supported by S-PACT modelling services

Read the whole case study

Sorodna ponudba

  • Product Picture Raman Rxn2 analyzer view from front showing left side Product Picture Raman Rxn2 analyzer view from front showing left side
    • F
    • L
    • E
    • X

    Raman Rxn2 analyzer

    Bridge your application from the laboratory to the process environment

    Nalaganje cene
    Cene trenutno niso na voljo
    Price on request
    from CHF ??.-
  • Product picture Raman Rxn-45 probe side view aiming right Product picture Raman Rxn-45 probe side view aiming right
    • F
    • L
    • E
    • X

    Raman Rxn-45 probe

    The ultimate in compatibility for bioprocess manufacturing

    Nalaganje cene
    Cene trenutno niso na voljo
    Price on request
    from CHF ??.-

  • Enostavni produkti

  • Lahka izbira, vgradnja in uporaba

Tehnična odličnost

Preprostost

  • Standardni produkti

  • Zanesljivi, robustni, nezahtevni za vzdrževanje

Tehnična odličnost

Preprostost

  • Vrhunski produkti

  • Visoko funkcionalni in praktični

Tehnična odličnost

Preprostost

  • Specialni produkti

  • Zasnovani za posebej zahtevne aplikacije

Tehnična odličnost

Preprostost

Spremenljivo

FLEX izbira Tehnična odličnost Preprostost
  • F
  • L
  • E
  • X

Segment Fundamental

Zadostite svojim osnovnim merilnim potrebam

Tehnična odličnost
Preprostost
  • F
  • L
  • E
  • X

Segment Lean

Obvladajte ključne procese na preprost način

Tehnična odličnost
Preprostost
  • F
  • L
  • E
  • X

Segment Extended

Optimirajte procese z inovativnimi tehnologijami

Tehnična odličnost
Preprostost
  • F
  • L
  • E
  • X

Segment Xpert

Imejte pod nadzorom najzahtevnejše aplikacije

Tehnična odličnost
Preprostost

Spremenljivo

Cenimo vašo zasebnost

Uporabljamo piškotke, da bi lahko izboljšali vašo izkušnjo med brskanjem, zbirali statistične podatke za izboljšanje delovanja spletnega mesta in zagotavljali prilagojene oglase ali vsebine.

Z izbiro "Sprejmi vse" se strinjate z našo uporabo piškotkov.
Za podrobnosti si oglejte naš Pravilnik o piškotkih .